ORIGINAL ARTICLE |
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Year : 2013 | Volume
: 40
| Issue : 1 | Page : 22-26 |
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Efficacy of botulinum toxin-A versus stabilization occlusal splint in treatment against temporomandibular disorders: a clinical and quantitative electromyographic study
Enas M. Shahine1, Ahmed M Abdel Hamid2, Yara A. Kammoun2
1 Department of Physical Medicine, Rheumatology and Rehabilitation, Faculty of Medicine, Alexandria University, Alexandria, Egypt 2 Department of Prosthodontics, Faculty of Dentistry, Alexandria University, Alexandria, Egypt
Correspondence Address:
Enas M. Shahine 39 Mostafa Kamel St, Bolkly, 21531 Alexandria Egypt
Source of Support: None, Conflict of Interest: None | Check |
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Aim
The aim of this study was to evaluate the efficacy of botulinum toxin-A (BTX-A) therapy compared with stabilization occlusal splint in treatment against temporomandibular disorders clinically and by electromyographic quantitative interference pattern analysis (QIPA).
Patients and methods
Twenty-four female patients with temporomandibular disorder symptoms and signs were enrolled in the study. The patients were randomly assigned into two groups. Patients in group 1 were injected with BTX-A in the affected masseter and temporalis muscles, whereas patients in group 2 were treated with occlusal splint therapy. Patients were evaluated at baseline and at 8 and 12 weeks using the anamnestic dysfunction index, measurement of maximum mouth opening, and surface electromyographic QIPA.
Results
On follow-up, anamnestic dysfunction index improvement and maximum mouth opening were significantly larger in the BTX-A group than in the splint group. BTX-A injections produced a general reduction in the QIPA parameters of masseter and temporalis muscles at the first follow-up, which increased slightly on the second assessment. In group 2, QIPA parameters were seen to have increased significantly at both assessments.
Conclusion
BTX-A injection is more advantageous than stabilization splint, provided it is administrated at appropriate doses. |
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